Chemotherapy & Infertility

The hallmark of a cancer cell, and what distinguishes it from many other cell types, is that it
continuously divides. This is the quality that chemotherapy drugs attempt to target as they try to
distinguish and kill cancer cells.

However, sperm cells are constantly dividing and developing as well, and they are thus easy
targets for chemotherapy drugs when a patient is undergoing cancer treatment. If all of the
immature cells in the testiles are damaged by the treatment, it could result in permanent
infertility if the damage prevents them from producing more sperm cells. In some cases, sperm
production will return after treatment ends.

There are many different types of chemotherapy drugs, some of which have a higher or lower
risk of causing male infertility. Although it may seem overwhelming, it is important to discuss
with one’s doctor, prior to beginning treatment, what effects it may have on one’s fertility, and to
learn about options for fertility preservation.

more posts

Melatonin and Sperm Quality

While the beneficial nature of melatonin, an endogenous anti-oxidant, has been known for decades, the investigation into the role of melatonin in fertility treatments, in

Round Spermatid Injection (ROSI)

Round Spermatid Injection (ROSI) The sperm develops, during spermatogenesis, from spermatogonia to spermatocytes, and then to round spermatids.  The round spermatids elongate, develop a tail

Medical History

The very first step in evaluating the fertility of a patient is receiving a thorough medical history.  The evaluating doctor will ask about previous evaluations,

Analysis of Testicular Biopsy

Non-obstructive azoospermia is diagnosed in cases where no sperm cells can be found in the ejaculate, yet no evidence of a blockage can be seen. 

Skip to content