Chemotherapy & Infertility

The hallmark of a cancer cell, and what distinguishes it from many other cell types, is that it continuously divides.  This is the quality that chemotherapy drugs attempt to target as they try to distinguish and kill cancer cells.

 

However, sperm cells are constantly dividing and developing as well, and they are thus easy targets for chemotherapy drugs when a patient is undergoing cancer treatment.  If all of the immature cells in the testiles are damaged by the treatment, it could result in permanent infertility if the damage prevents them from producing more sperm cells. In some cases, sperm production will return after treatment ends.

 

There are many different types of chemotherapy drugs, some of which have a higher or lower risk of causing male infertility. Although it may seem overwhelming, it is important to discuss with one’s doctor, prior to beginning treatment, what effects it may have on one’s fertility, and to learn about options for fertility preservation.  

 

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Capacitation

In order for the fully formed sperm cell to successfully activate and fertilize the oocyte, it must undergo several further steps in its maturation. The

Sexual Dysfunction & Male Infertility

Sexual dysfunction accounts for anywhere from 0.4-4.6% of male infertility cases, based on various studies. This category of male infertility includes erectile dysfunction, ejaculatory disorders,

Hamster Test

The hamster egg penetration test (HEPT) was first developed in the 1970s. It is observed on the observation that upon removal of the zona pellucida of

Sperm Retrieval Methods

Obstructive azoospermia (OA) occurs when something blocks the mature sperm’s ability to reach the ejaculate.  Instead, they remain “stuck” in the testis.  Several surgical techniques

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