Hormones and Male Sex Development

The male reproductive system is dependant on chemicals known as hormones, created by a system beginning in the brain’s hypothalamus. The hypothalamus acts as the bridge between the brain and the endocrine (hormonal) system.

The hypothalamus releases gonadotropin-releasing hormone (GnRH). This GnRH then reaches the pituitary gland, at the base of the brain, and stimulates the release of two gonadotropin hormones: luteinizing hormone (LH) and follicle-stimulating hormone (FSH).

Both LH and FSH affect the testes, however through their affinity to different testicular parts each has a distinctive effect. LH stimulates the production of testosterone (and other steroid hormones), while FSH is needed for sperm production.

This system is self-regulated and kept balanced using negative feedback loops. The amount of end product steroid hormones affect the hypothalamus, ensuring that the required amounts of hormones are being released.

more posts

Scraping Frozen Sperm

Partial thawing of a vial of cryopreserved sperm (or shaving) is sometimes applied as a measure to preserve sperm for further use, particularly in cases

Environmental factors

Studies have shown that certain environmental factors can have negative effects on male fertility. Overexposure to these factors, such as toxic chemicals or heat, can

Oligoasthenoteratozoospermia

Oligoasthenoteratozoospermia (OAT) is a common cause of male subfertility.  It is a condition which includes oligozoospermia, asthenozoospermia, and teratozoospermia.  In other words, the patient’s diagnosis

Preimplantation Genetic Diagnosis

Preimplantation genetic diagnosis, or PGD, is a diagnostic technique used together with IVF.  PGD is used in cases where the parents are at risk of

Skip to content